一、教育、工作經曆：

2023年3與月-至今，太阳成集团tyc234cc，講師

2018年9月-2022年12月，華南理工大學醫學院，博士

2015年9月-2018年6月，西南大學藥學院，碩士

2011年9月-2015年6月，河南中醫藥大學藥學院，學士

二、研究領域：

主要從事研究領域包括：探讨生物活性材料對突變p53、β澱粉樣等緻病蛋白調控的機制；從中藥中分離的小分子以及蛋白大分子活性成分抗腫瘤機制研究；以斑馬魚為模式生物進行藥物篩選、毒性發現以及安全性評價研究。

三、主要業績：

主持中央高校基本科學業務專項項目一項，參與國家自然科學基金面上及重點等多項項目的研究；在國内外SCI期刊發表學術論文10餘篇。

四、 代表性研究成果

1.  Wang Meimei, Yang Zhenyu, Song Yang, et al. Proteasomal and autophagy-mediated degradation of mutp53 proteins through mitochondria-targeting aggregation-induced-emission materials[J]. Acta Biomaterialia, 2022, 150: 402-412.

2. Wang Meimei, Ma Hang, Li Zhaoxing, et al. SPG-56 from Sweet potato Zhongshu-1 delayed growth of tumor xenografts in nude mice by modulating gut microbiota[J]. Journal of Functional Foods, 2019, 52: 291-301.

3. Wang Meimei, Ma Hang, Tian Cheng, et al. Bioassay-guided isolation of glycoprotein SPG-56 from sweet potato Zhongshu-1 and its anti-colon cancer activity in vitro and in vivo[J]. Journal of Functional Foods, 2017, 35: 315-324.

4. Tian Cheng, Wang Meimei, Liu Shanshan, et al. A new glycoprotein SPG-8700 isolated from sweet potato with potential anti-cancer activity against colon cancer[J]. Natural product research, 2019, 33(16): 2322-2328.

5. Jing Manman, Li Yafei, Wang Meimei, et al. Photoresponsive PAMAM‐Assembled Nanocarrier Loaded with Autophagy Inhibitor for Synergistic Cancer Therapy[J]. Small, 2021, 17(38): 2102295.

6. Ishimwe Nestor, Wei Pengfei, Wang Meimei, et al. Autophagy impairment through lysosome dysfunction by brucine induces immunogenic cell death (ICD)[J]. The American Journal of Chinese Medicine, 2020, 48(08): 1915-1940.

7. Ma Hang, Yu Yang, Wang Meimei, et al. Correlation between microbes and colorectal cancer: tumor apoptosis is induced by sitosterols through promoting gut microbiota to produce short-chain fatty acids[J]. Apoptosis, 2019, 24(1): 168-183.

8. Li Zhaoxing, Yu Yang, Wang Meimei, et al. Anti-breast cancer activity of SPG-56 from sweet potato in MCF-7 bearing mice in situ through promoting apoptosis and inhibiting metastasis[J]. Scientific reports, 2019, 9(1): 1-12.